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Specialist Allergy Diagnosis and Treatment in London

The London Allergy and Immunology Centre provides specialist diagnosis and treatment for a wide range of allergic conditions affecting both children and adults.

Our multidisciplinary team offers advanced allergy testing, personalised treatment plans and innovative therapies, helping patients manage allergic diseases safely and effectively.

We provide expert care for conditions including:

Anaphylaxis
✔ Food allergies
Allergic asthma
Hay fever (allergic rhinitis)
Insect venom allergies
Eczema (atopic dermatitis)
Chronic urticaria (hives)
✔ Drug allergies
✔ Symptomatic Dermatographism


Anaphylaxis

Anaphylaxis is a severe, potentially life-threatening allergic reaction. Hospital admissions for anaphylaxis in the UK increased by over 600% between 1992 and 2012, with biphasic reactions occurring in approximately 15% of cases.

Immediate treatment with intramuscular adrenaline can reduce mortality by up to 95%, yet many high-risk patients still lack accessible adrenaline auto-injectors.

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Our clinic provides specialist evaluation and risk management including:

✔ Personalised anaphylaxis risk assessment
✔ Tryptase testing and mast cell disorder screening
✔ Alpha-gal IgE testing for tick-associated allergy
✔ Comprehensive anaphylaxis action plans

Patients and caregivers receive access to:

✔ Emergency training videos
✔ Adrenaline auto-injector education
✔ Regular refresher training sessions

We also screen for underlying conditions such as hereditary alpha-tryptasemia (HaT) in unexplained or recurrent reactions.


Food Allergy

Food allergies affect approximately 7% of infants and children, with peanut and egg allergies accounting for the majority of early-onset cases.

Our clinic offers comprehensive diagnosis and management using advanced testing technologies.

Advanced Food Allergy Diagnosis

✔ Component-resolved diagnostics (CRD) such as Ara h 2 testing for peanut allergy
✔ Skin prick testing and specific IgE blood testing
✔ Oral food challenge testing under specialist supervision

These techniques improve diagnostic accuracy and can reduce unnecessary food avoidance.


Food Allergy Treatment and Immunotherapy

We provide oral immunotherapy (OIT) programmes designed to gradually increase tolerance to allergenic foods.

Our programmes achieve:

✔ Approximately 64% desensitisation in peanut allergy
✔ Reduced severity of allergic reactions
✔ Improved quality of life for families

Recent research shows anti-IgE therapy can reduce systemic reactions during oral immunotherapy by over 30%.

We also provide guidance on:

✔ Safe dietary reintroduction of foods such as baked milk or egg
✔ Allergy management during travel
✔ International continuity of care through the Global Allergy Network


Asthma and Allergic Respiratory Disease

Allergic asthma affects 5–12% of people in Europe, and pollen-related asthma admissions in the UK have increased significantly in recent years.

Early identification of allergic triggers plays an essential role in asthma management.

Allergy Testing for Asthma

Our diagnostic pathway includes:

✔ Skin prick testing for environmental allergens
✔ Component-resolved diagnostics
✔ FeNO testing to assess airway inflammation
✔ Spirometry for lung function evaluation


Advanced Asthma Treatments

For patients with allergic asthma we offer:

✔ Sublingual immunotherapy (SLIT) for pollen or house dust mite allergy
✔ Biologic therapies for severe asthma
✔ Environmental allergen reduction strategies

Clinical trials show that SLIT can reduce asthma exacerbations by 30–40%, while anti-IgE therapy can reduce severe exacerbations by up to 50%.


Hay Fever (Allergic Rhinitis)

Hay fever affects approximately one quarter of the UK population, often beginning during childhood or early adulthood.

Common triggers include:

✔ Grass pollen (June–July peak)
✔ Birch pollen (March–May peak)
✔ Tree and weed pollens

Climate change and urban planting trends have increased exposure to allergens such as oak and plane tree pollen.


Hay Fever Treatment Options

Our clinic provides personalised treatment including:

✔ Component-resolved allergy diagnostics
✔ Sublingual immunotherapy (SLIT) for grass, birch and house dust mite allergy
✔ Medication optimisation and avoidance strategies

After three years of immunotherapy treatment:

✔ Up to 70% symptom reduction is observed
✔ Risk of developing asthma in children is significantly reduced

Telemedicine follow-ups help improve adherence to treatment programmes.


Insect Venom Allergy

Severe allergic reactions to bee or wasp stings affect approximately 3% of adults.

Venom immunotherapy (VIT) is the most effective treatment and can reduce the risk of future reactions by up to 95%.

Our diagnostic pathway includes:

✔ Component-resolved venom testing
✔ Differentiation between true venom allergy and cross-reactive carbohydrate determinants
✔ Baseline tryptase testing for mast cell disorders

During treatment:

✔ Patients receive personalised adrenaline auto-injector training
✔ Over 90% of patients regain confidence in outdoor activities

Large local reactions to insect stings are common and usually do not require immunotherapy unless systemic symptoms occur.


Eczema (Atopic Dermatitis)

Eczema affects 15–20% of children in the UK and is strongly linked to the development of food allergies.

The dual allergen exposure hypothesis explains how allergens entering through damaged skin can lead to sensitisation.

Infants with moderate-to-severe eczema may have up to 50% increased risk of developing food allergies.


Eczema Management Strategies

Our clinic offers evidence-based eczema management including:

✔ Skin barrier repair strategies
✔ Early food allergen introduction guidance
✔ Allergy testing in high-risk infants
✔ Advanced biologic therapies for severe eczema

Genetic testing for filaggrin mutations may help identify patients at risk of persistent eczema.


Chronic Urticaria (Hives)

Chronic spontaneous urticaria affects approximately 1–2% of the population and can significantly impact quality of life.

Our specialist evaluation includes:

✔ Autoimmune screening
✔ Basophil activation and histamine release testing
✔ Component allergy diagnostics

Treatment options include:

✔ High-dose antihistamines
✔ Anti-IgE therapy for refractory cases
✔ Investigation for underlying infections or autoimmune conditions

Anti-IgE therapy can achieve remission in up to 60% of patients within six months.


Drug Allergy

More than 90% of suspected penicillin allergies are incorrect, yet incorrect allergy labels remain common and can lead to unnecessary antibiotic restrictions.

Our drug allergy de-labelling programme includes:

✔ Skin testing for common antibiotics
✔ Graded oral drug challenges
✔ Comprehensive allergy evaluation

This approach achieves over 95% clearance of incorrect allergy labels.

Drug allergy testing is performed following an initial consultation and may take place during specialist private hospital admission, where emergency support is available.


Telemedicine Allergy Consultations

We understand that allergy concerns often require prompt specialist advice.

Our telemedicine video and telephone consultations provide convenient access to experienced allergy specialists.

Patients benefit from:

✔ Same-day remote consultations
✔ Personalised advice and treatment planning
✔ Rapid triage of urgent allergy symptoms
✔ Arrangements for testing or in-clinic assessment if required

Telemedicine allows patients to receive expert allergy care from home or the workplace, with seamless access to further testing when needed.

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Dr Robert Boyle - MB ChB, MRCPCH, PhD